Profuse Bleeding is a symptom combo which causes large amounts of bleeding from open wounds. Haemophilia and Skin Lesions are required. The achievement Red Rain is earned for making it.
| Symptom Combos | |
|---|---|
| Standard Plagues | Red Rain ▪ Oops ▪ Projectile Vomiting ▪ Public Defecation ▪ Red Rain ▪ Swine Flu Walking Dead |
| Simian Flu | Assassin ▪ Blind Genius ▪ Discovery Channel ▪ Fly Magnet ▪ Red Ape Redemption ▪ Rude Awakening ▪ Zombie Panic |
| Necroa Virus | Bath Time ▪ Blood in the Air ▪ Boomer ▪ Cranial Dispersion ▪ Runner ▪ Spitter ▪ Tank ▪ Walking Contradiction ▪ Vampire Bat |
| Shadow Plague | Carpe Jugulum |
| Cure Mode | Report thy neighbour ▪ Rules are for losers ▪ We're here to help ▪ Happy Frogs ▪ Weapon X ▪ In it together ▪ Humans weren't meant to fly ▪ Shut down everything |
| Santa's Little Helper | On The Naughty List ▪ Ultimate Christmas |