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Skin Lesions

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Stn Skin Leisons
Skin Lesions


Breakdown in the epidermis causes large open wounds which significantly increases infectivity.

DNA cost


Severity increase




Infectivity increase


Next Symptom


Previous symptom


Skin Lesions is a tier 3 symptom. It greatly increases infectivity by causing large open wounds (large boils on the skin) to form. It is the only non-lethal symptom that equals Necrosis in infection rates, and the only non-lethal tier 3 symptom in the normal game. Skin Lesions are highly recommended when infecting people in a quick and effective manner.

Although not deadly, it is noticed in every plague type on all difficulties, regardless of what the player does (Other than Symbiosis 3, which is exclusive to the Parasite disease type).

It can be evolved with the tier 2 symptom Haemophilia to acquire the Profuse Bleeding symptom combo, which is slightly lethal and increases infection rates. This combo also unlocks the Red Rain achievement.

Profuse bleeding
Red rain

Red RainDiscover the Profuse Bleeding combo.

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