The following are strategies and tips for the Black Death scenario. Please feel free to add your own below:

Strategy 1Edit

Recommended genes:

  1. Start in India.
  2. Evolve the transmissions Rodent 1 and 2, Livestock 1 and 2, Bird 1 and 2, and Extreme Zoonosis
  3. Then, evolve the abilities Cold Resistance 1 and 2, and Drug Resistance 1 and 2 A player's plague should be spreading fairly quickly by now.
  4. Now, evolve the symptoms Skin Lesions (Optional), Pneumonic plague, Coughing, Sneezing, Pneumonia, and Pulmonary Oedema
  5. All countries should be infected by now. When the cure reaches 25%, evolve Genetic ReShuffle 1 and Drug Resistance 3. If the cure progress goes above 75%, evolve Hardened Reshuffle 1 and 2. If a player does not think their plague is killing fast enough and have some DNA points to spare, they should evolve Septicemic plague, Total Organ Failure and/or Dysentery.
  6. This will usually guarantee one biohazard if players follow all instructions; the strategist has gotten 2 biohazards using it. It will also work on Mega Brutal difficulty.
    Remember, with Extreme Zoonosis, even if a country is uninfected and has shut down its seaports/airports/land borders, players may still use infected animals in order to infect said country.


Strategy guides in Plague Inc. and Plague Inc: Evolved.
Speed Run/Bio-WeaponSpeed Run/PrionSpeed Run/Shadow PlagueStrategy Guide/Complete Mirror EarthStrategy guide/Film FanaticStrategy guide/Golden AgeStrategy guide/Not Just a Pretty FaceStrategy guide/Pirate PlagueStrategy Guide/Shadow PlagueStrategy guide/Shut Down EverythingStrategy guide/Volcanic AshStrategy Guide/Watery GraveStrategy guide/XenophobiaStrategy Guides/An Ape is for Life...Strategy Guides/BacteriaStrategy Guides/Banana SkinStrategy Guides/Big BangStrategy Guides/Bio-WeaponStrategy Guides/Black DeathStrategy Guides/Breathe DeepStrategy Guides/Chinese Nuclear RetaliationStrategy Guides/ChiroptophobiaStrategy Guides/Dead EndStrategy Guides/Don't Ask MeStrategy Guides/Due DiligenceStrategy Guides/Frozen VirusStrategy Guides/FungusStrategy Guides/Getting ColderStrategy Guides/Hide and SeekStrategy Guides/I am your FatherStrategy Guides/I never asked for thisStrategy Guides/Insane BoltStrategy Guides/It's a Trap!Strategy Guides/Mad Cow DiseaseStrategy Guides/Making AmendsStrategy Guides/Nano-VirusStrategy Guides/Necroa VirusStrategy Guides/Neurax WormStrategy Guides/No IdeaStrategy Guides/Non StarterStrategy Guides/Not Another Zombie GameStrategy Guides/ParasiteStrategy Guides/Patient Who?Strategy Guides/Peer PressureStrategy Guides/Plague in SpaceStrategy Guides/PrionStrategy Guides/Pus ExplosionStrategy Guides/Revenge of OsirisStrategy Guides/Russian Nuclear RetaliationStrategy Guides/SadomasochistStrategy Guides/Santa's Little HelperStrategy Guides/Shadow PlagueStrategy Guides/Shouldn't Keep PetsStrategy Guides/Simian FluStrategy Guides/Simian Flu Gene FarmingStrategy Guides/SmallpoxStrategy Guides/Starting CountryStrategy Guides/TeleportationStrategy Guides/Test This!Strategy Guides/VirusStrategy Guides/Who CaresStrategy Guides/Who needs brainsStrategy Guides/Who needs DEETStrategy Guides/Wolf Pack
Strategy guide

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