The following strategy is for the Simian Flu DLC in order to unlock its unique genes quickly. Feel free to add your own below:



  • ATP Boost
  • Aerocyte
  • Extremophile


  1. Play on Casual Difficulty.
  2. Before selecting the country, evolve Pharyngitis.
  3. Start your plague in Saudi Arabia.
  4. Evolve the following in that order:
    • Sneezing
    • Air 1&2
    • Drug Resistance 1
    • Cold Resistance 1
    • Water 1&2
    • Extreme Bioaresol
    • Drug Resistance 2
    • Cold Resistance 2
  5. Wait till the whole world is infected.
  6. When Cure Progression reaches 25%, immediately evolve Simian Neuro-Genesis.
  7. After the whole world is infected evolve:
    • Neuro-enhancement 1,2, &3
    • Total Brain Death
  8. After evolving Total Brain Death, evolve all other lethal symptoms.

Note: This strategy can also be used to get the No Idea achievement.

Note: Don't worry about mutations since they don't directly affect the outcome.

Strategy added by NinjaDogDB. Credit to the Yo It's Spicy Team. You can find the original strategy here .

Strategy guides in Plague Inc. and Plague Inc: Evolved.
Speed Run/Bio-WeaponSpeed Run/PrionSpeed Run/Shadow PlagueStrategy Guide/Complete Mirror EarthStrategy guide/Film FanaticStrategy guide/Golden AgeStrategy guide/Not Just a Pretty FaceStrategy guide/Pirate PlagueStrategy Guide/Shadow PlagueStrategy guide/Shut Down EverythingStrategy guide/Volcanic AshStrategy Guide/Watery GraveStrategy guide/XenophobiaStrategy Guides/An Ape is for Life...Strategy Guides/BacteriaStrategy Guides/Banana SkinStrategy Guides/Big BangStrategy Guides/Bio-WeaponStrategy Guides/Black DeathStrategy Guides/Breathe DeepStrategy Guides/Chinese Nuclear RetaliationStrategy Guides/ChiroptophobiaStrategy Guides/Dead EndStrategy Guides/Don't Ask MeStrategy Guides/Due DiligenceStrategy Guides/Frozen VirusStrategy Guides/FungusStrategy Guides/Getting ColderStrategy Guides/Hide and SeekStrategy Guides/I am your FatherStrategy Guides/I never asked for thisStrategy Guides/Insane BoltStrategy Guides/It's a Trap!Strategy Guides/Mad Cow DiseaseStrategy Guides/Making AmendsStrategy Guides/Nano-VirusStrategy Guides/Necroa VirusStrategy Guides/Neurax WormStrategy Guides/No IdeaStrategy Guides/Non StarterStrategy Guides/Not Another Zombie GameStrategy Guides/ParasiteStrategy Guides/Patient Who?Strategy Guides/Peer PressureStrategy Guides/Plague in SpaceStrategy Guides/PrionStrategy Guides/Pus ExplosionStrategy Guides/Revenge of OsirisStrategy Guides/Russian Nuclear RetaliationStrategy Guides/SadomasochistStrategy Guides/Santa's Little HelperStrategy Guides/Shadow PlagueStrategy Guides/Shouldn't Keep PetsStrategy Guides/Simian FluStrategy Guides/Simian Flu Gene FarmingStrategy Guides/SmallpoxStrategy Guides/Starting CountryStrategy Guides/TeleportationStrategy Guides/Test This!Strategy Guides/VirusStrategy Guides/Who CaresStrategy Guides/Who needs brainsStrategy Guides/Who needs DEETStrategy Guides/Wolf Pack
Strategy guide