Plague Inc. Wiki
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Plague final

Detailed map of Symptoms, with Infectivity, Severity, and Lethality values added.

Symptoms can be evolved through the Symptoms screen. Evolving a Symptom costs DNA points, but each evolution will make your pathogen increasingly deadly, infectious or frightening.

There are 6 symptoms available immediately, the others must be evolved after you have evolved a symptom in contact with it. These symtoms are: Nausea, Coughing, Rash, Imsomnia, Cysts, Anaemia. The most deadly are Dysentery, Total Organ Failure, and Necrosis.

Certain Symptoms will create Symptom Combos, which generally increase disease effectivity.

Name Effect Base Cost
Nausea Irritated stomach lining leads to discomfort. Slight chance of infection when kissing 2 DNA
Coughing Chance of infection by spreading pathogen into surroundings, especially in high density, urban areas 4 DNA
Rash The skin becomes blistered and painful, slightly increasing infectivity 3 DNA
Insomnia Inability to sleep makes people irritable and less productive 2 DNA
Cysts Painful lumps containing pockets of the pathogen. Slight chance of bursting which can spread disease 2 DNA
Anaemia Decrease in red blood cells or haemoglobin in the blood can lead to hypoxia in the organs 2 DNA
Vomiting The expulsion of infected material through projectile vomiting increases the risk of infection 4 DNA
Pneumonia Serious fluid build and discharge from the lungs. People in cold climates especially vulnerable 6 DNA
Sweating The loss of fluid through sweating increases infection rates due to poor hygiene. More dangerous in cold countries 7 DNA
Paranoia Irrational delusions and mental symptoms. Victims distrust of others makes them unlikely to seek treatment or cooperate with others 5 DNA
Hyper sensitivity Increases likelihood of allergic reactions which can distract the immune system. Rich nations particularly vulnerable. 2 DNA
Abscesses Pockets of infected flesh are painful and act as breeding grounds for the pathogen, increasing infection rates when burst. 2 DNA
Haemophilia Reduced blood clotting prevents wound healing. Pathogen able to spread through infected blood 3 DNA
Sneezing Fluid discharge through sneezing greatly increases infection rates. 5 DNA
Pulmonary Oedema Potentially fatal heart abnormality causes breakdown of respiratory system, releasing pathogens into the air. 7 DNA
Tumours Pathogens disrupt cell growth pathways, causing uncontrolled, eventually fatal tumour growth 11 DNA
Internal Haemorrhaging Flesh eating pathogens breaks down arterial membranes causing rapid internal bleeding and death 12 DNA
Fever Increase in temperature, contagiousness and severe dehydration, which can be fatal 9 DNA
Skin Lesions Breakdown in the epidermis causes large open wounds which significantly increases infectivity. 8 DNA
Seizures Random blackouts and fits reduce the patient's ability to function independently. Can be fatal 4 DNA
Inflammation Inflammation obstructs bodily processes. Swelling can obstruct breathing and be fatal 5 DNA
Diarrhoea Pathogen active in digestive tract, causing infection through faeces and potentially lethal dehydration. Poor countries V. vulnerable. 6 DNA
Dysentery A complete breakdown in the digestive tract causes infected sewage, dehydration, starvation and death 19 DNA
Insanity Neuropathic action of the pathogen in the frontal lobe causes severe emotional and behavioural abnormalities. Significantly harder to cure. 18 DNA
Necrosis Large swathes of infected tissue lose blood supply and become fatal sources of gangrene. Decomposed bodies remain a vector of transmission 27 DNA
Hemorrhagic Shock Failure of the heart to pump effectively causes oxygen deprivation, loss of consciousness and death 23 DNA
Paralysis Pathogen destroys motor neurons to cause paralysis. Significantly harder to cure and lethal 10 DNA
Coma Neuropathic effects in the brain stem cause loss of consciousness and sometimes death. Significantly harder to cure 21 DNA
Systemic Infection Pathogen affects multiple organ and tissue types, causing body-wide infections that spread fast and can be fatal 17 DNA
Pulmonary Fibrosis Scarring of the lungs causes shortness of breath and extreme coughing. Can be fatal when combined by intense exercise 6 DNA
Immune Suppression Pathogens attach to lymphocytes, suppressing immune system and allowing significantly greater freedom of mutation.Can be fatal. 12 DNA
Total Organ Failure Catastrophic cell death of multiple tissue types causes body-wide organ failure and rapid death 28 DNA
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